No, as there is no Regional Open game.
DLS only played NorCal Regional games in 2012 and 2013 then the game was eliminated. Since that time DLS has advanced directly from the NCS Section playoffs to the Open State Bowl game.
Since SF is in line for that spot this season, they‘d advance the same way. If SF somehow loses in the CCS Open, that opportunity would be up for grabs with Rocklin likely being in the driver seat should they win SJS D1 (with an undefeated record, of course).
The other 12 NorCal divisions would have to play a Regional game.