Salinas needs to initially focus on stopping the Serra running game, in my opinion, and take their chances with the pass. You can't allow them to remain balanced.
Can the Padres beat you through the air? Yes, but in a few of the games I've watched, they haven't really been the most patient. A lot of intermediate and deep passes that fell to the ground. Early in the year, they had some injuries on their OL and their passing game didn't entirely dominate.
For Salinas, they need to be effective through the air. I think they are now starting a sophomore running back, which could be tough against the Padres. I don't think they can afford more than one turnover in this game (the QB tends to be very good with his decisions, only 4 picks).
Sacred Heart Prep was receiving raves about their defense. Going into last week, they hadn't allowed more than 14 points in a game all season. The Cowboys had that by the end of the 1st quarter, en route to 28 total points. 28 was how many points the Gators had allowed in the previous 5 games combined.
Serra blasted Palma, but so did Salinas. After what had happened the previous week to them, once Serra jumped out to a lead, I have to sort of think that the Chieftains may not have had much fight in them at that point. Football can be a game of emotion and momentum, especially at this level. Against the Cowboys, Palma only mustered one screen pass for a long score (the other score came on a strange pick-6). At one point in the 2nd quarter, Coach Zenk for Salinas seemed so little concerned about the Chieftain offense that he actually went for it on 4th down from about their own 37. They didn't get it, but they stuffed the Palma offense immediately afterward and forced a punt. I do think that the star WRs will have to play more on defense than usual this weekend, though.
I think this game can be competitive, but I think we could also see Serra take the game comfortably. I've been saying all year that a team that can throw the ball well has at least a puncher's chance against most teams and Salinas does throw well.